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Study identifier: NCT03953144 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Synapse 3D With Intravascular Indocyanine Green

Condition: Non-small Cell Lung Cancer · Primary Neoplasm  ·  Sponsor: St. Joseph's Healthcare Hamilton

PhasePhase 1/Phase 2
Planned participants32
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

With the advent of CT screening for lung cancer, an increasing number of NSCLCs are being detected at very early stages, and the demand for pulmonary segmentectomy is rising rapidly. As such, there is a need to develop new surgical techniques to facilitate minimally invasive pulmonary segmentectomy, as segmentectomy may provide a number of significant advantages over lobectomy for patients presenting with early-stage lung cancer, or for patients unable to undergo a full lobectomy due to existing comorbidities. This study will provide the first case series using preoperative 3D anatomical planning (Synapse 3D) added to ICG and NIF-guided robotic segmentectomy to date and will be the first reported use of Synapse 3D-guided targeted pulmonary segmental resection in Canada. As lung cancer is the most frequently fatal cancer in North America, many thousands of patients will be able to benefit from this operation every year.

This description comes directly from the study's public registry record.

Talk to the study team

Peter R. A. Malik, BHSc (Honours)  ·  905-522-1155  ·  malikpr@mcmaster.ca

Yogita S Patel, BSc  ·  905-522-1155  ·  patelys@mcmaster.ca

Always discuss trial participation with your own doctor first.

Locations (1)

St. Josephs Healthcare HamiltonHamilton, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT03953144