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Study identifier: NCT03936647 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

The RISE Trial: A Randomized Trial on Intra-Saccular Endobridge Devices

Condition: Intracranial Aneurysm · Brain Aneurysm · Unruptured Cerebral Aneurysm  ·  Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

PhaseNA
Planned participants250
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Intracranial bifurcation aneurysms are commonly repaired with surgical and with endovascular techniques. Wide-necked bifurcation aneurysms (WNBA) are a difficult subset of aneurysms to successfully repair endovascularly, and a number of treatment adjuncts have been designed. One particularly promising innovation is the WEB (Woven EndoBridge), which permits placement of an intra-saccular flow diverting mesh across the aneurysm neck, but which does not require anti-platelet agent therapy. Currently, which treatment option leads to the best outcome for patients with WNBA remains unknown. There is a need to offer treatment with the WEB within the context of a randomized care trial, to patients currently presenting with aneurysms thought to be suitable for the WEB.

This description comes directly from the study's public registry record.

Talk to the study team

daniela E Iancu, MD  ·  514-890-8450  ·  daniela.iancu.med@ssss.gouv.qc.ca

Guylaine Gevry, BSc  ·  514-890-8000  ·  guylaine.gevry.chum@ssss.gouv.qc.ca

Always discuss trial participation with your own doctor first.

Locations (4)

University of Alberta HospitalEdmonton, Alberta, CanadaRecruiting
University of Manitoba HospitalWinnipeg, Manitoba, CanadaRecruiting
Hamilton Health Sciences - McMaster UniversityHamilton, Ontario, CanadaRecruiting
Centre Hospitalier de l'Université de MontréalMontreal, Quebec, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT03936647