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Study identifier: NCT03934372 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors

Condition: Acute Myeloid Leukemia · Accelerated Phase Chronic Myeloid Leukemia · Blast Phase Chronic Myeloid Leukemia  ·  Sponsor: Incyte Biosciences International Sàrl

PhasePhase 1/Phase 2
Planned participants70
Who can joinAll sexes, 1 Year to 17 Years
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, and efficacy of ponatinib in children aged 1 to \< 18 years with advanced leukemias, lymphomas, and solid tumors.

This description comes directly from the study's public registry record.

Talk to the study team

Incyte Corporation Call Center (ex-US)  ·  +800 00027423  ·  globalmedinfo@incyte.com

Always discuss trial participation with your own doctor first.

Locations (23)

Ghent University HospitalGhent, BelgiumRecruiting
Hopital Robert DebreParis, FranceRecruiting
Armand Trousseau HospitalParis, FranceRecruiting
Centre Hospitalier Universitaire de PoitiersPoitiers, FranceRecruiting
Chu de Rennes - Hospital SudRennes, FranceCompleted
Aou Policlinico S. Orsola-MalpighiBologna, ItalyRecruiting
Asst Degli Spedali Civili Di BresciaBrescia, ItalyRecruiting
Ospedale Pediatrico G. GasliniGenova, ItalyRecruiting
Comitato Etico Fondazione Irccs Istituto Nazionale Dei Tumori MilanoMilan, ItalyRecruiting
University of Milano BicoccaMonza, ItalyRecruiting
Aorn Santobono PausiliponNaples, ItalyNot Yet Recruiting
Comitato Di Bioetica Della Fondazione Irccs Policlinico San MatteoPavia, ItalyRecruiting

+ 11 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT03934372