Condition: Macular Degeneration, Dry · Primary Open-angle Glaucoma · Sponsor: Medical University of Vienna
It has been shown that reactions of human retinal photoreceptors to a light stimulus can be measured with custom-made, research prototype optical coherence tomography (OCT) systems. This can be used as a biomarker for the function of the photoreceptors. Due to the high technical demands on the system, however, the technique is currently not available for clinical purposes. In this pilot study a protocol to measure changes in retinal photoreceptor layer thickness before and after light stimulation shall be developed based on a commercial OCT system and newly developed algorithms. Other variables, such as circadian processes shall be investigated as well. After measurements in healthy volunteers, the protocol is planned to be applied in patients with primary open angle glaucoma (POAG) and age-related macular degeneration (AMD) to test for feasibility of the method in these patient groups.
This description comes directly from the study's public registry record.
Doreen Schmidl, MD,PhD · 0043140400 · doreen.schmidl@meduniwien.ac.at
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| Medical University of Vienna, Department of Clinical Pharmacology | Vienna, State of Vienna, Austria | Recruiting |
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Source record: clinicaltrials.gov/study/NCT03921931