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Study identifier: NCT03908684 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Ultrasound Spectroscopy as Early Indicators of Radiation Treatment Response in Prostate, Rectum and Head & Neck Cancers

Condition: Prostate Cancer · Head and Neck Cancer · Rectal Cancer  ·  Sponsor: Sunnybrook Health Sciences Centre

PhaseN/A
Planned participants320
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

Our objective in this study is to identify an optimal ultrasound spectroscopy parameter that can be used as an early predictor of pathological complete or partial response in men with prostate cancer and men and women with rectum and head and neck cancers receiving treatment radiotherapy. We have previously demonstrated that high-frequency ultrasound and spectroscopy, and recently conventional-frequency ultrasound and spectroscopy may be used to detect cell death in vitro, in situ and in vivo. The method can detect different forms of cell death and has been demonstrated to be sensitive to apoptotic, necrotic and mitotic cell death. The main goal, as described above, is to select the best ultrasound spectroscopy parameter to use as an early predictor of pathological complete response

This description comes directly from the study's public registry record.

Talk to the study team

Gregory J Czarnota, PhD, MD  ·  (416) 480-6128  ·  gregory.czarnota@sunnybrook.ca

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Locations (1)

Sunnybrook Health Sciences CentreToronto, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT03908684