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Study identifier: NCT03900793 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Losartan + Sunitinib in Treatment of Osteosarcoma

Condition: Osteosarcoma  ·  Sponsor: University of Colorado, Denver

PhasePhase 1
Planned participants41
Who can joinAll sexes, 10 Years to no upper limit
Healthy volunteersNo

About this study

This study is a Phase 1/1b clinical trial that aims to determine the Maximally Tolerated Dose of Losartan and Sunitinib Combination Therapy. Patients will first be accrued to the Dose Escalation phase of the study, using a 3+3 design. Medication dosages will increase until a maximally tolerated dose is found. Patients will then be accrued to the Dose Expansion phase of the trial, where efficacy of pre-determined dose will be preliminarily assessed.

This description comes directly from the study's public registry record.

Talk to the study team

Kelly Faulk, MD, MSCS  ·  720-777-6503  ·  kelly.faulk@childrenscolorado.org

Always discuss trial participation with your own doctor first.

Locations (4)

Children's Hospital Los AngelesLos Angeles, California, United StatesRecruiting
Children's Hospital ColoradoAurora, Colorado, United StatesRecruiting
University of Colorado HospitalAurora, Colorado, United StatesRecruiting
Children's Hospital of AtlantaAtlanta, Georgia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03900793