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Study identifier: NCT03894228 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Safety of IBD Drugs During Pregnancy and Breastfeeding: Mothers and Babies' Outcomes (DUMBO Registry)

Condition: Inflammatory Bowel Diseases · Pregnancy  ·  Sponsor: Grupo Espanol de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa

PhaseN/A
Planned participants1750
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a prospective, observational, multicenter registry, which will enrol pregnant women with IBD (CD, UC, or unclassified IBD) over 5 years in Spain. In addition, each incident gestation will be followed-up during pregnancy, and children born to those mothers will be followed-up over 4 years to determine the incidence of serious adverse events (such as alteration of developmental status, infections, neoplasia or any other serious adverse events) during the study period. In order to harmonize the inclusion of adverse events and complications, only serious adverse events will be registered . The main variable will be the development of serious infection in children as this is the outcome that had controversial results in previous studies.

This description comes directly from the study's public registry record.

Talk to the study team

María Chaparro, PhDMD  ·  913093911  ·  mariachs2005@gmail.com

María G Donday  ·  913093911  ·  mariagdonday@gmail.com

Always discuss trial participation with your own doctor first.

Locations (73)

Complejo Hospitalario Santiago de CompostelaSantiago de Compostela, A Coruña, SpainRecruiting
Hospital Universitario Reina SofíaCórdoba, Andalusia, SpainRecruiting
Hospital Clínico Universitario San CecilioGranada, Andalusia, SpainRecruiting
Hospital Infanta ElenaHuelva, Andalusia, SpainNot Yet Recruiting
Hospital Universitario Juan Ramón JimenezHuelva, Andalusia, SpainRecruiting
Hospital Regional Universitario de MálagaMálaga, Andalusia, SpainNot Yet Recruiting
Hospital Universitario Virgen de la VictoriaMálaga, Andalusia, SpainNot Yet Recruiting
Hospital San Juan de Dios del AljarafeSeville, Andalusia, SpainNot Yet Recruiting
Hospital Universitario Virgen del RocíoSeville, Andalusia, SpainRecruiting
Hospital San JorgeHuesca, Aragon, SpainNot Yet Recruiting
Hopsital Universitario Miguel ServetZaragoza, Aragon, SpainNot Yet Recruiting
Hospital Clínico Universitario Lozano BlesaZaragoza, Aragon, SpainRecruiting

+ 61 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT03894228