Condition: Bladder Adenocarcinoma · Bladder Clear Cell Adenocarcinoma · Bladder Mixed Adenocarcinoma · Sponsor: National Cancer Institute (NCI)
This phase II trial studies how well cabozantinib works in combination with nivolumab and ipilimumab in treating patients with rare genitourinary (GU) tumors that has spread from where it first started (primary site) to other places in the body. Cabozantinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving cabozantinib, nivolumab, and ipilimumab may work better in treating patients with genitourinary tumors that have no treatment options compared to giving cabozantinib, nivolumab, or ipilimumab alone.
This description comes directly from the study's public registry record.
Contact details are listed per location below or on the registry record.
Always discuss trial participation with your own doctor first.
| University of Alabama at Birmingham Cancer Center | Birmingham, Alabama, United States | Active Not Recruiting |
| Anchorage Associates in Radiation Medicine | Anchorage, Alaska, United States | Suspended |
| Anchorage Radiation Therapy Center | Anchorage, Alaska, United States | Suspended |
| Alaska Breast Care and Surgery LLC | Anchorage, Alaska, United States | Suspended |
| Alaska Oncology and Hematology LLC | Anchorage, Alaska, United States | Suspended |
| Alaska Women's Cancer Care | Anchorage, Alaska, United States | Suspended |
| Anchorage Oncology Centre | Anchorage, Alaska, United States | Suspended |
| Katmai Oncology Group | Anchorage, Alaska, United States | Suspended |
| Providence Alaska Medical Center | Anchorage, Alaska, United States | Suspended |
| Kingman Regional Medical Center | Kingman, Arizona, United States | Suspended |
| Cancer Center at Saint Joseph's | Phoenix, Arizona, United States | Active Not Recruiting |
| Mayo Clinic Hospital in Arizona | Phoenix, Arizona, United States | Recruiting |
+ 570 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT03866382