Condition: Alzheimer Disease · Cognitive Impairment · Cognitive Decline · Sponsor: University of California, Irvine
The purpose of this research study is to understand the factors that underlie changes in thinking and memory with increasing age. The investigators will test the usefulness of MRI, PET, and cognitive testing in detecting subtle changes in the brain that precede cognitive decline. An addendum to this study includes additional PET scans to examine the relationship between tau protein in the brain and cognitive decline. Tau is a protein that is known to form tangles in the areas of the brain important for memory, and these tau tangles are a hallmark of Alzheimer's disease. This sub-study research aims to look at the tau accumulation in the brain using an investigational drug called MK-6240, which is a radio tracer that gets injected prior to a positron emission tomography (PET) scan.
This description comes directly from the study's public registry record.
Evelyn Chang, BA · 949-824-0904 · beacon@uci.edu
Novelle Meza, BS · 949-824-5049 · njmeza@uci.edu
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| University of California, Irvine | Irvine, California, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT03860857