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Study identifier: NCT03858972 Synced from ClinicalTrials.gov · July 28, 2026
● Terminated

Tesetaxel Plus Reduced Dose of Capecitabine in Patients With HER2 Negative, HR Positive, LA/MBC

Condition: Breast Cancer  ·  Sponsor: Odonate Therapeutics, Inc.

PhasePhase 2
Planned participants152
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

CONTESSA 2 is a multinational, multicenter, Phase 2 study of tesetaxel in patients with HER2 negative, HR positive, locally advanced or metastatic breast cancer (LA/MBC) not previously treated with a taxane. The primary objective of the study is to establish the efficacy of tesetaxel plus a reduced dose of capecitabine based on objective response rate (ORR) as assessed by an Independent Radiologic Review Committee (IRC). 152 patients were enrolled.

This description comes directly from the study's public registry record.

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Contact details are listed per location below or on the registry record.

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Locations (25)

Innovative Clinical Research InstituteWhittier, California, United States
Rocky Mountain Cancer CenterLakewood, Colorado, United States
Sarah Cannon Research Institute - Florida Cancer SpecialistsFort Myers, Florida, United States
Florida Cancer Specialists and Research InstituteSt. Petersburg, Florida, United States
Dana-Farber Cancer InstituteBoston, Massachusetts, United States
New York Cancer and Blood SpecialistsEast Setauket, New York, United States
West Cancer CenterGermantown, Tennessee, United States
Texas Oncology - Baylor Charles A. Sammons Cancer CenterDallas, Texas, United States
Virginia Oncology AssociatesNorfolk, Virginia, United States
Border Medical OncologyAlbury, New South Wales, Australia
Hopital Maisonneuve-RosemontMontreal, Canada
Center Hospitalier de Montreal CHUM McPeak SiroisMontreal, Canada

+ 13 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT03858972