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Study identifier: NCT03854110 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Trial to Evaluate Safety, Tolerability, and Preliminary Efficacy of Misetionamide (GP-2250) as Monotherapy or in Combination With Gemcitabine

Condition: Ovarian Cancer  ·  Sponsor: Persevere Therapeutics Inc.

PhasePhase 1
Planned participants80
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a phase 1 dose escalation trial of monotherapy misetionamide (also known as GP-2250) currently enrolling patients with platinum-resistant ovarian cancer (PROC) into Part 2 of the study. Part 1 of the study evaluating misetionamide in combination with gemcitabine in subjects with advanced pancreatic cancer previously treated with 5-fluorouracil-based chemotherapy completed enrolment.

This description comes directly from the study's public registry record.

Talk to the study team

Kathryn M Martin, PharmD  ·  8455481808  ·  kmmartin@glenmereresearch.com

Seymour Fein, MD  ·  610-922-1910  ·  seymour.fein@perseveretherapeutics.com

Always discuss trial participation with your own doctor first.

Locations (4)

Rush University Medical CenterChicago, Illinois, United StatesRecruiting
University of Kansas Cancer CenterFairway, Kansas, United StatesRecruiting
Beth Israel Deaconess Medical CenterBoston, Massachusetts, United StatesRecruiting
Abramson Cancer Center at the University of PennsylvaniaPhildelphia, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03854110