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Study identifier: NCT03850366 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

HLA-Haploidentical Peripheral Blood Stem Cell Transplantation With Post-transplant Cyclophosphamide and Bortezomib

Condition: Hematological Malignancy  ·  Sponsor: Henry Ford Health System

PhasePhase 2
Planned participants15
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

Now haplo stem cell transplant using bone marrow or peripheral blood is becoming more feasible with better regimens to prevent graft versus host disease (GVHD) like post transplant cyclophosphamide , tacrolimus, mycophenolate . Recently Bortezomib has also been shown to inhibit dendritic cells maturation and function and possesses a number of other favorable immunomodulatory effect that can prevent GVHD and help enhance immune reconstitution. this study is to assess the engraftment rate in patients with hematologic malignancies who need allogeneic stem cell transplant but do not have a suitable matched related or unrelated stem cell donor and will get T-cell replete HLA-Haploidentical allogeneic peripheral stem cell transplantation using post transplant Cyclophosphamide and bortezomib

This description comes directly from the study's public registry record.

Talk to the study team

shatha farhan  ·  313 713 3910  ·  sfarhan1@hfhs.org

Always discuss trial participation with your own doctor first.

Locations (1)

Henry Ford hospitalDetroit, Michigan, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03850366