Condition: Neonatal Thrombocytopenia · Sponsor: Boston Children's Hospital
This is a prospective observational study that was designed with the following two Specific Aims: 1. To determine whether the Immature Platelet Fraction percentage (IPF%) and the Immature Platelet Count (IPC) are better predictors of bleeding than the platelet count alone in neonates of different gestational and post-conceptional ages and with different etiologies of thrombocytopenia; and 2. To characterize the effects of neonatal thrombocytopenia and platelet transfusions (PLT Tx) on bleeding and on markers of systemic inflammation, thrombosis, and neutrophil extracellular traps (NET) formation in neonates with different underlying conditions.
This description comes directly from the study's public registry record.
Martha Sola-Visner, MD · 617-919-4845 · martha.sola-visner@childrens.harvard.edu
Vanessa J Young, RN, BA · 617-355-8330 · vanessa.young@childrens.harvard.edu
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| Beth Israel Deaconess Medical Center | Boston, Massachusetts, United States | Recruiting |
| Boston Children's Hospital | Boston, Massachusetts, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT03848923