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Study identifier: NCT03847649 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Phase II Study of Durvalumab Treatment - Substudy A: In Patients Who Discontinued Prior Checkpoint Therapy Due to Immune Related Toxicity - Substudy B: For Continued Treatment (+/- Tremelimumab) of Patients Previously Enrolled to Completed CCTG Studies

Condition: Cancer  ·  Sponsor: Canadian Cancer Trials Group

PhasePhase 2
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

I238A: The purpose of this study is to find out what effects being treated with durvalumab has on cancer. The researchers doing this study also want to evaluate if prednisone (a type of steroid), when given together with durvalumab, can reduce any side effects. I238B: The purpose of this study is to allow patients previously enrolled on a completed CCTG trial to continue treatment with durvalumab (+/- tremelimumab)

This description comes directly from the study's public registry record.

Talk to the study team

Pierre-Olivier Gaudreau  ·  613-533-6430  ·  p-ogaudreau@ctg.queensu.ca

Always discuss trial participation with your own doctor first.

Locations (11)

Cross Cancer InstituteEdmonton, Alberta, CanadaRecruiting
BCCA - KelownaKelowna, British Columbia, CanadaRecruiting
BCCA - VancouverVancouver, British Columbia, CanadaRecruiting
Regional Health Authority B, Zone 2Saint John, New Brunswick, CanadaRecruiting
Juravinski Cancer Centre at Hamilton Health SciencesHamilton, Ontario, CanadaRecruiting
Waterloo Regional Health Network (WRHN)Kitchener, Ontario, CanadaRecruiting
Ottawa Hospital Research InstituteOttawa, Ontario, CanadaRecruiting
University Health NetworkToronto, Ontario, CanadaRecruiting
Windsor Regional Cancer CentreWindsor, Ontario, CanadaRecruiting
CHUM-Centre Hospitalier de l'Universite de MontrealMontreal, Quebec, CanadaRecruiting
Saskatoon Cancer CentreSaskatoon, Saskatchewan, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT03847649