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Study identifier: NCT03828773 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

PTX3-targeted Antifungal Prophylaxis

Condition: Candidiasis · Fungal Infection · Acute Myeloid Leukemia  ·  Sponsor: Bochud Pierre-Yves

PhaseNA
Planned participants410
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a prospective genetically-stratified randomized double-blind event-driven multicentre clinical trial to assess the efficacy of posaconazole-based antifungal prophylaxis allocation strategies for patients with acute myeloid leukemia who receive induction chemotherapy. Allocation strategy based on an invasive mold infection genetic risk will be double-blinded.

This description comes directly from the study's public registry record.

Talk to the study team

Pierre-Yves Bochud, MD  ·  0041 213144379  ·  Pierre-Yves.Bochud@chuv.ch

Always discuss trial participation with your own doctor first.

Locations (9)

Ghent University HospitalGhent, Belgium, BelgiumTerminated
AZ Sint-Jan HospitalBruges, BelgiumRecruiting
University Hospital Leuven (UZ Leuven)Leuven, BelgiumRecruiting
Henri Mondor HospitalCréteil, Île-de-France Region, FranceRecruiting
Cantonal Hospital AarauAarau, Aarau, SwitzerlandRecruiting
University Hospital BaselBasel, Basel, SwitzerlandRecruiting
Cantonal Hospital HFRFribourg, Canton of Fribourg, SwitzerlandRecruiting
University Hospital of Geneva (HUG)Geneva, Canton of Geneva, SwitzerlandRecruiting
University Hospital of Lausanne / Centre Hospitalier Universitaire Vaudois (CHUV)Lausanne, Canton of Vaud, SwitzerlandRecruiting

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Source record: clinicaltrials.gov/study/NCT03828773