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Study identifier: NCT03807401 Synced from ClinicalTrials.gov · July 29, 2026
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A Technical Innovation of Prismatic Adaptation Test in Healthy Subject, in Favour of Autonomy and Independence in Daily Life Following a Brain Injury

Condition: Healthy Volunteers  ·  Sponsor: Hospices Civils de Lyon

PhaseNA
Planned participants480
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersYes

About this study

Unilateral neglect is a neuropsychological disorder reflected by a disturbance in the spatial exploration and distribution of directed attention affecting the contralateral part of space and body relatively to the brain lesion. The chronic aspect of this pathology leads to a poor progression following rehabilitation and a decreased independence of patients in daily life. Thus, it is necessary to set up efficient and long lasting therapies for unilateral neglect patients to improve their daily quality of life. Prismatic adaptation is now a classical method which allows patients to improve their neglect through corrective pointing movements in response to a lateral displacement of the visual field. A large and growing body of literature has investigated prismatic adaptation as a very promising rehabilitation method, improving both visuomotor and cognitive features of unilateral neglect. However, its effects are somehow irregular and clinical applications of this method are still limited. The necessity for patients to come to the hospital to take advantage of prismatic adaption sessions draws some limitations about our knowledge concerning 1) the temporal dynamic of prism adaptation effects on a long-term basis and 2) the optimal duration of treatment (most of the time constrained by the hospitalization duration) and its therapeutical effects on a very long-term basis. Moreover, a large number of patients also suffer from motor deficits which reduce the possibility to optimize t…

This description comes directly from the study's public registry record.

Talk to the study team

Yves ROSSETTI, MD  ·  04 72 91 34 12  ·  yves.rossetti@inserm.fr

Alessandro FARNE, PhD  ·  04 72 91 34 12  ·  Alessandro.farne@inserm.fr

Always discuss trial participation with your own doctor first.

Locations (1)

Lyon Neuroscience Research CenterBron, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT03807401