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Study identifier: NCT03802695 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Phase 1 Study of Orca-Q in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

Condition: Acute Myeloid Leukemia · Myelodysplastic Syndromes · Mixed Phenotype Acute Leukemia  ·  Sponsor: Orca Biosystems, Inc.

PhasePhase 1
Planned participants300
Who can joinAll sexes, 12 Years to 78 Years
Healthy volunteersNo

About this study

This study will evaluate the safety, tolerability, and efficacy of engineered donor grafts ("OrcaGraft"/"Orca-Q") in participants undergoing allogeneic hematopoietic cell transplant (alloHCT) transplantation for hematologic malignancies.

This description comes directly from the study's public registry record.

Talk to the study team

Tamara Zharkevich, MD, PhD  ·  650-246-9601  ·  info@orcabiosystems.com

James S McClellan, MD PhD  ·  650-246-9601  ·  info@orcabiosystems.com

Always discuss trial participation with your own doctor first.

Locations (12)

City of HopeDuarte, California, United StatesRecruiting
UC DavisSacramento, California, United StatesRecruiting
Stanford Health CareStanford, California, United StatesRecruiting
Moffitt Cancer CenterTampa, Florida, United StatesRecruiting
Emory UniversityAtlanta, Georgia, United StatesActive Not Recruiting
The University of Kansas HospitalKansas City, Kansas, United StatesWithdrawn
John Theurer Cancer Center at Hackensack University Medical CenterHackensack, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesRecruiting
Ohio State UniversityColumbus, Ohio, United StatesActive Not Recruiting
University of Texas MD Anderson Cancer CenterHouston, Texas, United StatesRecruiting
Fred Hutchinson Cancer CenterSeattle, Washington, United StatesRecruiting
Froedtert Memorial Lutheran HospitalMilwaukee, Wisconsin, United StatesWithdrawn

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Source record: clinicaltrials.gov/study/NCT03802695