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Study identifier: NCT03786549 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Pediatric -Adult Care Transition Program of Patients With Sickle Cell Disease

Condition: Sickle Cell Disease  ·  Sponsor: Hospices Civils de Lyon

PhaseNA
Planned participants196
Who can joinAll sexes, 16 Years to 17 Years
Healthy volunteersNo

About this study

Background The pediatric-adult care transition is a risk-disrupting time for patients with chronic disease. This care transition takes place during adolescence; a period of psychological upheavals and adaptations of family roles. During this period, medication adherence is non-optimal and absenteeism at medical appointments is high. Sickle cell disease (SCD) is the first genetic disease detected in France. It is chronic disease characterized by frequent painful vaso-occlusive crises (VOC) requiring emergency hospitalization when they are severe. Other serious complications are acute chest syndromes (ACS) and stroke. In order to improve the health status of teenagers with sickle cell disease, it is necessary to anticipate this care transition and to involve the pediatric and adult sectors. The biopsychosocial health approach and the Social-Ecological Model of Adolescent and Young Adult Readiness to Transition (SMART) describe a care transition integrating bioclinical and psychosocial factors such as integration of the patient's family, education on disease and therapeutics, psychological management of pain and medico-social orientation. The pediatric-adult transition program proposed is based on this biopsychosocial approach. It aims to improve the health status of adolescents with SCD, their quality of life and the use of health care service. Objective of the study To assess the impact of a pediatric-adult transition program on the incidence of sickle-cell-related complic…

This description comes directly from the study's public registry record.

Talk to the study team

Alexandra GAUTHIER VASSEROT, DR  ·  04 69 16 65 72  ·  alexandra.gauthier@ihope.fr

Sandrine TOUZET, Dr  ·  04 72 11 57 61  ·  sandrine.touzet@chu-lyon.fr

Always discuss trial participation with your own doctor first.

Locations (8)

CHU de Fort de FranceFort-de-France-La Martinique, La Martinique, FranceNot Yet Recruiting
Centre Hospitalier Intercommunal de CreteilCréteil, FranceNot Yet Recruiting
Hôpital MondorCréteil, FranceNot Yet Recruiting
Hôpital BicêtreLe Kremlin-Bicêtre, FranceNot Yet Recruiting
Hospices Civils de LyonLyon, FranceRecruiting
Hôpital Européen Georges PompidouParis, FranceNot Yet Recruiting
Hôpital NeckerParis, FranceNot Yet Recruiting
Centre Hospitalier de PontoisePontoise, FranceNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT03786549