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Study identifier: NCT03781752 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Carboxylesterase 1 Genetic Variation and Methylphenidate in ADHD

Condition: ADHD · Attention Deficit Hyperactivity Disorder  ·  Sponsor: Icahn School of Medicine at Mount Sinai

PhasePhase 4
Planned participants500
Who can joinAll sexes, 6 Years to 17 Years
Healthy volunteersNo

About this study

The study team will determine the association between d,l-methylphenidate (MPH) therapeutic outcomes in ADHD patients and genetic variants of CES1 and reveal key associations between CES1 genotypes and the PK and PD of MPH.

This description comes directly from the study's public registry record.

Talk to the study team

Beth Krone, PhD  ·  212-241-8012  ·  beth.krone@mssm.edu

John Markowitz, PharmD

Always discuss trial participation with your own doctor first.

Locations (4)

University of FloridaGainesville, Florida, United StatesRecruiting
Icahn School of Medicine at Mount SinaiNew York, New York, United StatesRecruiting
Cincinnati Children's Hospital Medical CenterCincinnati, Ohio, United StatesCompleted
Seattle Children's HospitalSeattle, Washington, United StatesTerminated

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Source record: clinicaltrials.gov/study/NCT03781752