Condition: Healthy Elderly Individuals With High LDL-cholesterol or Risk of Cardiovascular Disease · Sponsor: Yonsei University
One of the most effective drug in the primary prevention of cardiovascular disease is statins. The protective effects of statin on developement of cardiovascular disease has been demonstrated in elderly individuals. Since side effects of statin are more common in elderly individuals than in younger individuals, clinical guidelines recommend that use of low intensity statin is considered in elderly individuals. However, there are few randomized clinical trials evaluating the safety and efficacy of different intensity statins in elderly individuals. This is a multicenter, prospective, randomized clinical trial to compare efficacy and safety between low and high intensity statin for primary prevention of cardiovacsular disease in elderly individuals.
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| Division of Cardiology, Cardiovascular Center, Severance Hospital, Yonsei University College of Medicine | Seoul, South Korea | Recruiting |
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Source record: clinicaltrials.gov/study/NCT03770312