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Study identifier: NCT03756961 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Effects of an Opioid Free/Sparing Care Pathway for Patients Undergoing Obesity Surgery

Condition: Obesity · Pain, Postoperative  ·  Sponsor: Göteborg University

PhaseNA
Planned participants220
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The opioid consumption has exploded in the western world, and for some patient populations such as obese patients, patients with sleep apnoea or patients undergoing cancer treatment, opioid-sparing/ opioid-free strategies could have positive effects on outcomes. Studies suggest that opioids could have opioid-induced immunosuppression, induce chronic post-operative pain syndrome and hyperalgesia in addition to the more well-known side effects such as respiratory depression, nausea, bladder, and bowel dysfunction. Hence, new studies are needed on the impact of person-centered care programs that combine pharmaceutical and non-pharmaceutical strategies to reduce the adverse short and long-term effects of opioid therapy. The overall aim is to evaluate the short-, medium- and long-term effects of opioid-free care pathways with or without person-centred care compared to conventional opioid-based treatment in patients undergoing obesity surgery. Specific aims 1. Determine the effects of opioid-free care with or without person-centred care compared with conventional opioid-based general anaesthesia on the cognitive and physical quality of recovery after surgery up to 24 months after surgery (short-term: postoperative to discharge, medium-term: 14 days, 3 months, long-term: 6 months, 12 months and 24 months). 2. Describe the clinical monitoring trend regarding nociceptive response intraoperatively between opioid-free and conventional care. 3. Map the impact of opioid-free anaesthesi…

This description comes directly from the study's public registry record.

Talk to the study team

Axel Wolf, RN, PhD  ·  +46709355364  ·  axel.wolf@gu.se

Always discuss trial participation with your own doctor first.

Locations (2)

Lindesberg HospitalLindesberg, Region Örebro, SwedenRecruiting
Sahlgrenska University hospital/ Östra hopsitalGothenburg, VG, SwedenRecruiting

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Source record: clinicaltrials.gov/study/NCT03756961