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Study identifier: NCT03746769 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Improving Islet Transplantation Outcomes With Gastrin for Type I Diabetes

Condition: Diabetes Mellitus, Type 1  ·  Sponsor: City of Hope Medical Center

PhasePhase 1/Phase 2
Planned participants20
Who can joinAll sexes, 18 Years to 68 Years
Healthy volunteersNo

About this study

This clinical study will evaluate the safety and effectiveness of Gastrin treatment with islet transplantation to help patients with difficult to control type 1 diabetes make insulin again and improve blood sugar control. This study involves two investigational (experimental) products not yet approved by the U.S. Food and Drug Administration (FDA) as a treatment for any disease: 1. Human allogenic islet cells (islet cells from a deceased, unrelated human donor) 2. Gastrin-17 (Gastrin) - a hormone secreted by the gut

This description comes directly from the study's public registry record.

Talk to the study team

Arthur Riggs Diabetes & Metabolism Research Institute at COH  ·  1-866-44-ISLET(1-866-444-7538)  ·  Islets@coh.org

Always discuss trial participation with your own doctor first.

Locations (1)

City of Hope Medical CenterDuarte, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03746769