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Study identifier: NCT03713879 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Comparative Effectiveness Between Indomethacin and Pancreatic Stenting in the Prevention of Post ERCP Pancreatitis

Condition: Post ERCP Pancreatitis  ·  Sponsor: Chinese University of Hong Kong

PhasePhase 3
Planned participants1734
Who can joinAll sexes, 18 Years to 99 Years
Healthy volunteersNo

About this study

Post ERCP pancreatitis (PEP) occurs in 4 to 5% of patients and is associated with significant morbidities and occasional mortalities. The use of rectall administered indomethacin and pancreatic duct stent (PDS) placement have independently been proven to reduce PEP. The comparative effectiveness of the two methods has however not been studied. It is argued that in the context of indomethacin, the placement of a PDS is unnecessary. Advocates for PDS insertion however believe that mechanical decompression of the pancreatic duct is critical in the prevention of pancreatitis. The investigators propose a multi-centre randomised controlled trial to compare the use of rectal indomethacin to PDS insertion in high risk patients in the prevention of PEP.

This description comes directly from the study's public registry record.

Talk to the study team

James LAU, MD  ·  35051411  ·  laujyw@surgery.cuhk.edu.hk

RAYMOND TANG, MD  ·  35052640  ·  raymondtang@cuhk.edu.hk

Always discuss trial participation with your own doctor first.

Locations (7)

Endoscopy centreXi'an, Shaanxi, ChinaRecruiting
Eastern Hepatobiliary Surgery Hospital,Endoscopy centreShanghai, Shanghai Municipality, ChinaRecruiting
Endoscopy centreShanghai, Shanghai Municipality, ChinaNot Yet Recruiting
Endoscopy centreTianjin, Tianjin Municipality, ChinaRecruiting
Endoscopy centreHangzhou, Zhejiang, ChinaRecruiting
Endoscopy Centre, Prince of Wales HospitalHong Kong, Hong Kong, Hong KongRecruiting
2. Chulalongkorn University and King Chulalongkorn Memorial HospitalBangkok, ThailandRecruiting

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Source record: clinicaltrials.gov/study/NCT03713879