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Study identifier: NCT03683433 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Enasidenib and Azacitidine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia and IDH2 Gene Mutation

Condition: Acute Bilineal Leukemia · Acute Biphenotypic Leukemia · Chronic Myelomonocytic Leukemia  ·  Sponsor: M.D. Anderson Cancer Center

PhasePhase 2
Planned participants50
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This phase II trial studies how well enasidenib and azacitidine work in treating patients with IDH2 gene mutation and acute myeloid leukemia that has come back (recurrent) or does not respond to treatment (refractory). Enasidenib and azacitidine may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.

This description comes directly from the study's public registry record.

Talk to the study team

Courtney DiNardo  ·  713-794-1141  ·  cdinardo@mdanderson.org

Always discuss trial participation with your own doctor first.

Locations (1)

M D Anderson Cancer CenterHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03683433