Condition: Beta Lactam Resistant Bacterial Infection · Enterobacteriaceae Infections · Bacteremia · Sponsor: Rambam Health Care Campus
Data regarding optimal treatment for extended-spectrum beta-lactamase (ESBL) producing Enterobacteriaceae blood-stream infection are lacking. Observational studies show conflicting results when comparing treatment with combination beta-lactam-beta-lactamase inhibitor and carbapenems. The investigators aim to evaluate the effect of definitive treatment with meropenem vs. piperacillin-tazobactam on the outcome of patients with bacteremia due to cephalosporin-non-susceptible Enterobacteriaceae. The investigators hypothesize that piperacillin-tazobactam is non-inferior to meropenem.
This description comes directly from the study's public registry record.
Mical Paul, MD · 972-4-7772991 · m_paul@rambam.health.gov.il
Roni Bitterman, MD · 972-4-7772991 · ro_oren@rambam.health.gov.il
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| University of Calgary, Cumming School of Medicine, O'Brien Institute for Public Health | Calgary, Alberta, Canada | Recruiting |
| Surrey Memorial Hospital - Fraser Health Authority | Surrey, British Columbia, Canada | Recruiting |
| Eastern Health | St. John's, Newfoundland and Labrador, Canada | Recruiting |
| Kingston General Hospital | Kingston, Ontario, Canada | Recruiting |
| Jewish Genral Hospital | Montreal, Quebec, Canada | Recruiting |
| McGill University Health Centre | Montreal, Quebec, Canada | Recruiting |
| Rambam Health Care Campus | Haifa, Israel, Israel | Recruiting |
| Soroka Medical Center | Beersheba, Israel | Recruiting |
| Hadassah Medical Center | Jerusalem, Israel | Recruiting |
| Meir Medical Center | Kfar Saba, Israel | Recruiting |
| Sanz Medical Center-Laniado Hospital | Netanya, Israel | Recruiting |
| Rabin Medical Center, Beilinson Campus | Petah Tikva, Israel | Recruiting |
+ 2 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT03671967