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Study identifier: NCT03671889 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

ExAblate Blood-Brain Barrier (BBB) Disruption for the Treatment of Alzheimer's Disease

Condition: Alzheimer Disease  ·  Sponsor: InSightec

PhaseNA
Planned participants50
Who can joinAll sexes, 50 Years to 85 Years
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the safety and efficacy of the ExAblate Model 4000 Type 2.0 System as a tool to disrupt the blood-brain barrier (BBB) in patients with probable Alzheimer's Disease (AD).

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (10)

Delray Medical Center & Florida Atlantic UniversityDelray Beach, Florida, United StatesRecruiting
Broward Health Medical Center & The University of FloridaFort Lauderdale, Florida, United StatesRecruiting
University of Florida Health ShandsGainesville, Florida, United StatesRecruiting
Baptist Health South Florida & Florida International UniversityMiami, Florida, United StatesRecruiting
Advent HealthOrlando, Florida, United StatesRecruiting
Tampa General HospitalTampa, Florida, United StatesRecruiting
Weill Cornell MedicineNew York, New York, United StatesActive Not Recruiting
The Ohio State University -Wexner Medical CenterColumbus, Ohio, United StatesActive Not Recruiting
University of Texas Southwestern Medical CenterDallas, Texas, United StatesActive Not Recruiting
West Virginia University Rockefeller Neuroscience CenterMorgantown, West Virginia, United StatesActive Not Recruiting

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Source record: clinicaltrials.gov/study/NCT03671889