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Study identifier: NCT03667326 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Postpartum Low-Dose Aspirin and Preeclampsia

Condition: Preeclampsia Postpartum  ·  Sponsor: Columbia University

PhasePhase 2
Planned participants100
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersYes

About this study

The purpose of this research study is to find out whether women with severe preeclampsia taking low-dose aspirin (LDA) for 3 weeks post-delivery will experience an improvement in endothelial function (measured as flow-mediated dilation - FMD) and severity of disease, as the effects of preeclampsia can persist postpartum. Women diagnosed with severe preeclampsia prior to delivery will be enrolled and randomized to receive either low-dose aspirin (81mg) or placebo to take daily for up to 3 weeks post-delivery. Exploratory objective includes healthy control postpartum patients without preeclampsia and not on LDA during pregnancy or postpartum in comparison with the primary study population affected by preeclampsia with severe features.

This description comes directly from the study's public registry record.

Talk to the study team

Aleha Aziz, MD, MPH  ·  646-678-0289  ·  aa4065@cumc.columbia.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Columbia University Irving Medical CenterNew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03667326