Condition: Major Depressive Disorder · Alzheimer Disease · Mild Cognitive Impairment · Sponsor: Rotman Research Institute at Baycrest
In this study, the investigators will be examining the effects of the deep repetitive transcranial magnetic stimulation (rTMS) using the H1 coil in patients over the age of 60 diagnosed with mild to early-moderate Alzheimer's disease (AD) or mild cognitive impairment (MCI) and comorbid Major Depressive Disorder (MDD) who have been unable to tolerate or failed to respond to antidepressant medications. The coil was designed to stimulate deeper regions of the left dorsolateral prefrontal cortex (DLPFC). Based on prior research, the investigators propose that active stimulation with the H1 coil for 4 weeks may result in significant remission rates and will be tolerable and safe.
This description comes directly from the study's public registry record.
Amanda Rahmadian, BSc · 416-785-2500 · dtms@research.baycrest.org
Linda Mah, MD · 416-785-2500 · preventad@research.baycrest.org
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| Rotman Research Institute at Baycrest | Toronto, Ontario, Canada | Recruiting |
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Source record: clinicaltrials.gov/study/NCT03665831