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Study identifier: NCT03657524 Synced from ClinicalTrials.gov · July 29, 2026
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Speckle Tracking Echocardiography for the Prediction of Weaning Failure

Condition: Weaning Failure of Mechanical Ventilation  ·  Sponsor: Assistance Publique Hopitaux De Marseille

PhaseNA
Planned participants110
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

Deciding the optimal timing for extubation in patients who are mechanically ventilated can be challenging, and traditional weaning predictor tools are not accurate. Recent studies suggest that isolated sonographic assessment of the respiratory and cardiac function (ie diastolic function and filling pressure), in mechanically ventilated patients may assist in identifying patients at risk of weaning failure. Recently, the association of conventional echocardiography and lung ultrasound showed promising results for the prediction of post extubation distress. Speckle Tracking is an emerging tool in intensive care medicine that has never been investiguated for the prediction of weaning failure. It could early detects diastolic dysfunction and and elevated filling pressure. Of more, speckle tracking is known to be less operator dependant. The main objective of our study is to evaluate the diagnosis accuracy of speckle tracking echocardiography performed during a weaning trial to predict weaning failure. The secondary objectives are to assess the diagnosis accuracy of combined heart and lung ultrasound to predict weaning failure.

This description comes directly from the study's public registry record.

Talk to the study team

Laurent ZIELESKIEWICZ  ·  04 91 96 53 77  ·  laurent.zieleskiewicz@ap-hm.fr

Always discuss trial participation with your own doctor first.

Locations (1)

Assistance Publique Hôpitaux de MarseilleMarseille, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT03657524