Condition: Sickle Cell Anemia · Beta-thalassemia Major · Diamond-blackfan Anemia · Sponsor: Paul Szabolcs
The purpose of this study is to evaluate what effect, if any, mismatched unrelated volunteer donor and/or haploidentical related donor stem cell transplant may have on severe sickle cell disease and other transfusion dependent anemias. By using mismatched unrelated volunteer donor and/or haploidentical related donor stem cells, this study will increase the number of patients who can undergo a stem cell transplant for their specified disease. Additionally, using a T-cell depleted approach should reduce the incidence of graft-versus-host disease which would otherwise be increased in a mismatched transplant setting.
This description comes directly from the study's public registry record.
Paul Szabolcs, MD · 412-692-6225 · paul.szabolcs@chp.edu
Shawna McIntyre, RN · 412-692-5552 · mcintyresm@upmc.edu
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| Children's Hospital of Pittsburgh of UPMC | Pittsburgh, Pennsylvania, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT03653338