Condition: Mild Cognitive Impairment(MCI) · Alzheimer Disease, Late Onset · Familial Alzheimer Disease (FAD) · Sponsor: Capital Medical University
The aim of this study is to establish and perfect the China Cognition and Aging Study (China COAST) cohort, to clarify the epidemiology, influencing factors, genetic characteristics, pathogenesis, disease characteristics and diagnosis and treatment status of dementia and its subtypes in China. It is of great significance to establish a relatively comprehensive national database of cognitive disorders, improve the clinical diagnosis and treatment level of cognitive disorders, and formulate prevention and treatment strategies for dementia. The primary aims of China COAST are as follows: 1. To use the prospective cohort to establish a large database research platform, so as to provide comprehensive epidemiological data, clinical and neuropsychological evaluation data, biological samples, and laboratory tests and imaging data. 2. To update the prevalence and incidence rate of dementia and its subtypes every 2-3 years, and clarify the conversion pattern from normal elderly to MCI and from MCI to dementia. 3. To explore the known or unknown protective and risk factors of dementia and its major subtypes (AD, VaD, other dementia). 4. To discover new pathogenic genes and susceptible genes of dementia and its major subtypes (AD and VaD), as well as new mutation sites of known pathogenic genes. To study the genetic variation, mutation and polymorphism of PSEN1, PSEN2, APP and APOE genes in dementia patients, and to understand their distribution and roles in the pathogenesis. 5. To stud…
This description comes directly from the study's public registry record.
Jianping Jia, Doctor · jiajp@vip.126.com
Always discuss trial participation with your own doctor first.
| The First Affiliated Hospital of Anhui Medical University | Hefei, Anhui, China | Recruiting |
| Beijing Geriatric Hospital | Changping, Beijing Municipality, China | Recruiting |
| Beijing Chao Yang Hospital | Chaoyang, Beijing Municipality, China | Recruiting |
| China-Japan Friendship Hospital | Chaoyang, Beijing Municipality, China | Recruiting |
| Dongfang Hospital Affiliated to Beijing University of Chinese Medicine | Fengtai, Beijing Municipality, China | Recruiting |
| Chinese PLA General Hospital | Haidian, Beijing Municipality, China | Recruiting |
| Fu Xing Hospital, Capital Medical University | Haidian, Beijing Municipality, China | Recruiting |
| Peking University Third Hospital | Haidian, Beijing Municipality, China | Recruiting |
| Peking Union Medical College Hospital | Xicheng, Beijing Municipality, China | Recruiting |
| Peking University First Hospital | Xicheng, Beijing Municipality, China | Recruiting |
| Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | Yuzhong, Chongqing Municipality, China | Recruiting |
| The Second Affiliated Hospital of Chongqing Medical University | Yuzhong, Chongqing Municipality, China | Recruiting |
+ 53 more locations — full list on the registry record.
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT03653156