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Study identifier: NCT03649048 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Low-Dose Weekly vs High-Dose Cisplatin

Condition: Locally Advanced Head and Neck Squamous Cell Carcinoma  ·  Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

PhaseNA
Planned participants100
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is a prospective open-label randomized clinical trial. Following informed consent eligible LASCCHN patients (n=100) planned for CRT will be stratified by tumor p16 status and then randomized in a 1:1 fashion to either concurrent HD cisplatin or concurrent weekly LD cisplatin.

This description comes directly from the study's public registry record.

Talk to the study team

Sara Kuruvilla, MD  ·  (519)685-8500  ·  sara@kuruvilla@lhsc.on.ca

Always discuss trial participation with your own doctor first.

Locations (3)

Juravinski Cancer CentreHamilton, Ontario, CanadaRecruiting
London Regional Cancer ProgramLondon, Ontario, CanadaActive Not Recruiting
Sunnybrook Health Sciences CentreToronto, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT03649048