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Study identifier: NCT03610763 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Harnessing Neuroplasticity to Enhance Functional Recovery During Chronic Recovery From Upper Extremity Nerve Repair

Condition: Hand Transplantation · Peripheral Nerve Injuries · Neurologic Rehabilitation  ·  Sponsor: University of Missouri-Columbia

PhaseNA
Planned participants180
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study adopts a strategy that has arisen from basic neuroscience research on facilitating adaptive brain plasticity and applies this to rehabilitation to improve functional recovery in peripheral nervous system injuries (including hand transplantation, hand replantation, and surgically repaired upper extremity nerve injuries). The technique involves combining behavioral training with transcranial direct current stimulation (tDCS)-a non-invasive form of brain stimulation capable of facilitating adaptive changes in brain organization.

This description comes directly from the study's public registry record.

Talk to the study team

Scott H Frey, Ph.D., Ed.M.  ·  573-882-4572  ·  freylab@missouri.edu

Always discuss trial participation with your own doctor first.

Locations (3)

Christine Kleinert Institute for Hand & MicrosurgeryLouisville, Kentucky, United StatesRecruiting
University of MissouriColumbia, Missouri, United StatesRecruiting
Washington University School of MedicineSt Louis, Missouri, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03610763