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Study identifier: NCT03589729 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Dexrazoxane Hydrochloride in Preventing Heart-Related Side Effects of Chemotherapy in Participants With Blood Cancers

Condition: Acute Myeloid Leukemia · Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive · Blasts 10 Percent or More of Bone Marrow Nucleated Cells  ·  Sponsor: M.D. Anderson Cancer Center

PhasePhase 2
Planned participants100
Who can joinAll sexes, 12 Years to no upper limit
Healthy volunteersNo

About this study

This phase II trial studies how well dexrazoxane hydrochloride works in preventing heart-related side effects of chemotherapy in participants with blood cancers, such as acute myeloid leukemia, myelodysplastic syndrome, chronic myeloid leukemia, and myeloproliferative neoplasms. Chemoprotective drugs, such as dexrazoxane hydrochloride, may protect the heart from the side effects of drugs used in chemotherapy, such as cladribine, idarubicin, cytarabine, and gemtuzumab ozogamicin, in participants with blood cancers.

This description comes directly from the study's public registry record.

Talk to the study team

Maro Ohanian  ·  713-792-2631  ·  mohanian@mdanderson.org

Always discuss trial participation with your own doctor first.

Locations (1)

M D Anderson Cancer CenterHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03589729