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Study identifier: NCT03587701 Synced from ClinicalTrials.gov · July 29, 2026
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Effects of Anakinra in Subjects With Corticosteroid-resistant/Intolerant Meniere's Disease and Autoimmune Inner Ear Disease

Condition: Autoimmune Inner Ear Disease · Meniere's Disease  ·  Sponsor: Northwell Health

PhasePhase 2
Planned participants57
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

A Phase II randomized, placebo controlled study design of anakinra (Kineret) in corticosteroid-resistant or intolerant Meniere's disease (CR-MD)and corticosteroid-resistant or intolerant autoimmune inner ear disease (CR-AIED) patients. Patients will be randomized by a 2:1 allocation to anakinra or placebo for 42 continuous days. After day 42, a second placebo-controlled period will begin for an additional 42 days. This will be followed by a 264 day observation period, during which, hearing declines may be re-treated with anakinra after 30 days following the initial drug.

This description comes directly from the study's public registry record.

Talk to the study team

Ginny Mullooly, RN  ·  718-470-7974  ·  gmullool@northwell.edu

Andrea Vambutas, MD  ·  718-470-7550  ·  avambuta@northwell.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Northwell Health, Hearing& Speech CenterNew Hyde Park, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03587701