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Study identifier: NCT03586609 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Venetoclax, Cladribine, Low Dose Cytarabine, and Azacitidine in Treating Patients With Previously Untreated Acute Myeloid Leukemia

Condition: Acute Myeloid Leukemia  ·  Sponsor: M.D. Anderson Cancer Center

PhasePhase 2
Planned participants145
Who can joinAll sexes, 50 Years to no upper limit
Healthy volunteersNo

About this study

This phase II trial studies how well venetoclax, cladribine, low dose cytarabine, and azacitidine work in treating patients with acute myeloid leukemia that has previously not been treated. Drugs used in chemotherapy, such as venetoclax, cladribine, and low dose cytarabine, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Azacitidine may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving venetoclax, cladribine, low dose cytarabine induction followed by cladribine, low dose cytarabine, and azacitidine consolidation may work better in treating patients with acute myeloid leukemia.

This description comes directly from the study's public registry record.

Talk to the study team

Tapan Kadia  ·  713-563-3534  ·  kadia@mdanderson.org

Always discuss trial participation with your own doctor first.

Locations (1)

M D Anderson Cancer CenterHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03586609