Condition: CVI - Common Variable Immunodeficiency · Sponsor: IMMUNOe Research Centers
Patients receiving intravenous immunoglobulin (IVIG) therapy for primary immunodeficiency and neurologic conditions may experience adverse drug reactions (ADRs). The mechanism of the ADR is unknown. Currently, the standard practice for these patients is to change from IV to subcutaneous IG (SCIG) but because of the need of immunomodulation or patient preference, SCIG may not be an option. Data has shown that some levels of complement decrease from pre- to post-infusion of IVIG. This study is to determine if replacing this complement protein may ameliorate ADRs.
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| IMMUNOe Research Centers | Centennial, Colorado, United States | — |
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Source record: clinicaltrials.gov/study/NCT03576469