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Study identifier: NCT03555851 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Factors Affecting Post-transplant Cyclophosphamide (PTCy) Efficacy

Condition: Leukemia, Not Otherwise Specified · Leukemia, Other  ·  Sponsor: Wake Forest University Health Sciences

PhaseN/A
Planned participants120
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study will examine the influence of donor and recipient pharmacogenetics (PG), drug pharmacokinetics (PK), and T cell phenotypes and how it may permit a tailored dosing strategy to improve the therapeutic index of post-transplant cyclophosphamide (PTCy) and optimize the graft versus tumor effect, while minimizing acute and chronic graft versus host disease (GVHD).

This description comes directly from the study's public registry record.

Talk to the study team

Elizabeth Parke  ·  980-442-2011  ·  elizabeth.parke@atriumhealth.org

Always discuss trial participation with your own doctor first.

Locations (1)

Levine Cancer InstituteCharlotte, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03555851