Condition: Brain Metastases · Sponsor: Canadian Cancer Trials Group
Stereotactic radiosurgery (SRS) is a commonly used treatment for brain tumors. It is a one-day (or in some cases two day), out-patient procedure during which a high dose of radiation is delivered to small spots in the brain while excluding the surrounding normal brain. Whole brain radiation therapy with hippocampal avoidance (HA-WBRT) is when radiation therapy is given to the whole brain, while trying to decrease the amount of radiation that is delivered to the area of the hippocampus. The hippocampus is a brain structure that is important for memory. Memantine is a drug that is given to help relieve symptoms that can be caused by WBRT, including problems with memory and other mental symptoms. Health Canada, the regulatory body that oversees the use of drugs in Canada, has not approved the sale or use of memantine in combination with WBRT to treat this kind of cancer, although they have allowed its use in this study.
This description comes directly from the study's public registry record.
Chris O'Callaghan · 613-533-6430 · cocallaghan@ctg.queensu.ca
Always discuss trial participation with your own doctor first.
| University of Arizona Cancer Center-Orange Grove Campus | Tucson, Arizona, United States | Recruiting |
| University of Arizona Cancer Center-North Campus | Tucson, Arizona, United States | Recruiting |
| City of Hope Corona | Corona, California, United States | Recruiting |
| City of Hope Comprehensive Cancer Center | Duarte, California, United States | Recruiting |
| City of Hope at Irvine Lennar | Irvine, California, United States | Recruiting |
| UC San Diego Moores Cancer Center | La Jolla, California, United States | Suspended |
| City of Hope Antelope Valley | Lancaster, California, United States | Recruiting |
| UC Irvine Health/Chao Family Comprehensive Cancer Center | Orange, California, United States | Active Not Recruiting |
| Kaiser Permanente-Rancho Cordova Cancer Center | Rancho Cordova, California, United States | Active Not Recruiting |
| Rohnert Park Cancer Center | Rohnert Park, California, United States | Active Not Recruiting |
| The Permanente Medical Group-Roseville Radiation Oncology | Roseville, California, United States | Active Not Recruiting |
| South Sacramento Cancer Center | Sacramento, California, United States | Active Not Recruiting |
+ 74 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT03550391