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Study identifier: NCT03546829 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Safety Trial of Antimicrobial Therapy and Precision Radiation Therapy in Patients With Oligoprogressive Non-small Cell Lung Cancer

Condition: Early Stage Non-Small Cell Lung Cancer  ·  Sponsor: Abramson Cancer Center at Penn Medicine

PhasePhase 1
Planned participants10
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The first phase of this study was an open label, randomized pilot study. Enrollment for this phase is now complete. The second phase is a single arm phase 1 safety study. Patients planned to undergo precision hypofractionated radiation to all sites of oligoprogression will receive vancomycin for 1 week before RT and for 1 month after start of RT, and asked to provide stool and blood samples as outlined in the Safety Trial study table.

This description comes directly from the study's public registry record.

Talk to the study team

Ching Lai  ·  267-250-9244  ·  ching.lai@pennmedicine.upenn.edu

RadOnc Clinical Research Unit  ·  radonccru@pennmedicine.upenn.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of PennsylvaniaPhiladelphia, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03546829