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Study identifier: NCT03538665 Synced from ClinicalTrials.gov · July 29, 2026
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The DETECT Study: Discovery and Evaluation of Testing for Endometrial and Ovarian Cancer in Tampons

Condition: Endometrial Cancer · Endometrial Cancer Precursors · Ovarian Cancer  ·  Sponsor: University of Alabama at Birmingham

PhaseN/A
Planned participants1500
Who can joinFemale, 18 Years to 99 Years
Healthy volunteersYes

About this study

BACKGROUND: Endometrial cancer is a common and deadly cancer for women. It is getting more common and deadly because risk factors like age and obesity are increasing. Also, this cancer is becoming more common and deadly for black women than white women. Researchers want to find better ways to take samples and test them for this cancer. They want to study this for a racially diverse population. One way to take samples might be from a tampon. If identified early, endometrial cancer can be highly curable; however, the earliest stages may be asymptomatic, and clinical symptoms are often missed. Combining sensitive molecular testing approaches with non-invasive sampling techniques may to lead to the development of novel endometrial cancer early detection approaches with the potential to overcome disparities in access to care and time to diagnosis and treatment. In contrast to endometrial cancer, ovarian cancer is typically detected at advanced stages with poor survival since symptoms manifest only late in the disease process and are very unspecific. Racial disparities in ovarian cancer incidence and mortality are also much less pronounced. Racial disparities can manifest particularly when screening, symptom appraisal and early detection, and effective treatment interventions have important roles in determining outcomes of cancers. OBJECTIVES: The purpose of this study is to see if it is possible and acceptable for individuals to have an endometrial or ovarian sample collected …

This description comes directly from the study's public registry record.

Talk to the study team

Rebecca C Arend, MD, MSPH  ·  (205) 934-5370  ·  rarend@uabmc.edu

Megan A Clarke-Corso, Ph.D.  ·  (240) 276-7823  ·  megan.clarke@nih.gov

Always discuss trial participation with your own doctor first.

Locations (1)

University of Alabama at BirminghamBirmingham, Alabama, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03538665