Condition: Solid Cancers · Sponsor: Institut Claudius Regaud
This is a translational, open-label, multi-site, prospective cohort study aiming to identify and to monitor immunological biomarkers associated with therapeutic response to immune checkpoints blockade (ICB), in patients with multiple types of advanced (unresectable and/or metastatic) solid cancers. The study will be conducted on a population of patients receiving ICB (anti-PD-1 or anti-PD-L1 or anti-CTLA4, alone or in combination) in the context of either routine care or a clinical study protocol. Patients with any of the following tumor types may be enrolled in the trial: * Non-Small Cell Lung Cancer (NSCLC), * Head and neck cancer, * Melanoma, * Bladder cancer, * Other tumor types when Immuno-Oncology agent is expected to be efficient or when a clinical trial is an option. For each included patient, tumor biopsy specimens and blood samples will be collected at different time points. All included patients will be followed-up until progression. After this date, survival data will be collected.
This description comes directly from the study's public registry record.
Jean-Pierre DELORD, MD · 05 31 15 55 00 · delord.jean-pierre@iuct-oncopole.fr
Always discuss trial participation with your own doctor first.
| Hopital Larrey | Toulouse, France | Recruiting |
| Institut Universitaire Du Cancer de Toulouse - Oncopole | Toulouse, France | Recruiting |
| Chu Rangueil | Toulouse, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT03514368