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Study identifier: NCT03511807 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Acoustic and Electrical Stimulation for the Treatment of Tinnitus

Condition: Tinnitus  ·  Sponsor: University of California, Irvine

PhaseNA
Planned participants100
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

Tinnitus, or ringing in the ears, affects 10% to 30% of the population. Of those, 20% have tinnitus bothersome enough to seek medical attention. In many people, tinnitus can significantly affect the quality of life. At this point in time, there is no effective treatment or cure available for tinnitus. It has been found that electrical stimulation of the inner ear can reduce and in some cases eliminate tinnitus. The purpose of this research is to investigate both acoustic and electrical stimulation of the inner ear as a possible treatment of tinnitus. In both acoustic and electrical testing conditions, the subjects will be instructed to be familiar with a 0-10 ranking scale of loudness. In acoustic testing, the stimulus will be presented through headphones in a noiseless environment, and the subject will be asked to report on the loudness of the presented sound and the level of the tinnitus at 20-second intervals. If the subject cannot perceive the presence of the tinnitus, a value of zero will be assigned. A typical sound will be presented for 3 to 6 minutes. Loudness will be reported for 1 to 4 minutes after stimulus offset to measure the presence and duration of residual inhibition. Electrical stimulation will be delivered to the inner ear in three ways, 1. using a cochlear implant (implant placed in the inner ear to replace hearing function), 2. Using an electrode placed in the ear canal, and 3. using a small needle inserted through the ear drum. Various electrical sign…

This description comes directly from the study's public registry record.

Talk to the study team

Hamid Djalilian, MD  ·  tinnitus@uci.edu

William Pu, MS  ·  entclinicalstu@hs.uci.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Hamid R. DjalilianIrvine, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03511807