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Study identifier: NCT03492671 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Testing the Combination of Two Approved Chemotherapy Drugs and Radiation Prior to Surgery in Localized Pancreatic Cancer

Condition: Pancreas Adenocarcinoma · Resectable Pancreatic Cancer  ·  Sponsor: Loma Linda University

PhasePhase 2
Planned participants30
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this phase 2 research study is to determine whether a combination of chemotherapy drugs plus radiation therapy, given before surgery in resectable pancreactic cancer, can help to increase the chances of surgeons achieving and R0 resection. The chemotherapy drugs used are gemcitabine and nab-paclitaxel. These drugs are both approved by the FDA for use in treating adults with pancreatic adenocarcinoma. The investigational portion of this study is providing the chemotherapy drugs and radiation therapy before surgery. Primary Endpoint, R) resection rate ≥70%. Secondary Endpoints, Disease free survival, Overall survival , Perioperative mortality and morbidity.

This description comes directly from the study's public registry record.

Talk to the study team

Naveenraj Solomon, MD  ·  909-558-5498  ·  nsolomon@llu.edu

Shagufta Shaheen, MD  ·  909-558-4050  ·  sshaheen@llu.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Loma Linda University HealthLoma Linda, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03492671