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Study identifier: NCT03465592 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Trial of Nivolumab Following Partially Human Leukocyte Antigen (HLA) Mismatched BMT in Children & Adults With Sarcoma

Condition: Sarcoma · Solid Tumor, Adult · Solid Tumor, Childhood  ·  Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

PhasePhase 1/Phase 2
Planned participants39
Who can joinAll sexes, 12 Months to 40 Years
Healthy volunteersNo

About this study

This research is being done to find out if an investigational drug, Nivolumab, can be safely administered after a "half-matched" (haplo) bone marrow transplant (BMT), and if the investigational drug will help to prevent or delay relapse or progression of sarcomas. In this study investigators will also be trying to learn more about how the investigational drug changes blood and/or tumors. Participants are eligible for this trial if they have recently undergone a "half-matched" (haplo) bone marrow transplant and have either relapsed or are at high risk to relapse.

This description comes directly from the study's public registry record.

Talk to the study team

Megan Petrycki, RN  ·  410-955-0432  ·  mpetryc1@jhmi.edu

Tammy Scott, RN  ·  410-614-5990  ·  scottta@jhmi.edu

Always discuss trial participation with your own doctor first.

Locations (4)

Johns Hopkins All Children's HospitalSt. Petersburg, Florida, United StatesActive Not Recruiting
Johns Hopkins HospitalBaltimore, Maryland, United StatesRecruiting
Albert Einstein College of Medicine, Children's Hospital at MontefioreThe Bronx, New York, United StatesRecruiting
New York Medical Center/ Maria Fareri Children's HospitalValhalla, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03465592