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Study identifier: NCT03463954 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Confirmatory Clinical Evaluation of Novilase® Laser Therapy for Focal Destruction of Malignant Breast Tumors

Condition: Malignant Neoplasm of Breast  ·  Sponsor: Novian Health Inc.

PhaseNA
Planned participants122
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

Prior to this confirmatory pivotal study, the multicenter Br-002 feasibility study was completed. 98% of tumors less than or equal to 15mm were completely ablated in one procedure.This study will evaluate Novilase for the focal destruction of malignant tumors of the breast that are less than or equal to 15 mm against a performance goal for the standard of care, lumpectomy. The ASBrS' goal of less than 20% retreatment by 2020 was selected as a representative performance goal, i.e., 80.0%, and is consistent with published effectiveness rates for lumpectomy.

This description comes directly from the study's public registry record.

Talk to the study team

Eugene Bajorinas  ·  3122667200  ·  ebajorinas@novianhealth.com

Chip Appelbaum  ·  3122667200  ·  info@novianhealth.com

Always discuss trial participation with your own doctor first.

Locations (13)

City of HopeDuarte, California, United StatesWithdrawn
UC San Diego HealthLa Jolla, California, United StatesRecruiting
Eisenhower HealthRancho Mirage, California, United StatesRecruiting
Yale UniversityNew Haven, Connecticut, United StatesRecruiting
Walter Reed National Military Medical CenterBethesda, Maryland, United StatesWithdrawn
Summit HealthFlorham Park, New Jersey, United StatesNot Yet Recruiting
Buffalo General Medical CenterBuffalo, New York, United StatesRecruiting
St. Elisabeth-Krankenhaus Köln-HohenlindCologne, GermanyRecruiting
Ichilov | Tel Aviv Sourasky Medical CenterTel Aviv, IsraelRecruiting
Breast Centre ZurichZurich, SwitzerlandTerminated
University Hospital ZurichZurich, SwitzerlandRecruiting
Charing Cross Hospital, Imperial College Healthcare NHS TrustLondon, United KingdomRecruiting

+ 1 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT03463954