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Study identifier: NCT03454035 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Ulixertinib/Palbociclib in Patients With Advanced Pancreatic and Other Solid Tumors

Condition: Tumor, Solid · Pancreatic Cancer · Melanoma  ·  Sponsor: UNC Lineberger Comprehensive Cancer Center

PhasePhase 1
Planned participants45
Who can joinAll sexes, 18 Years to 99 Years
Healthy volunteersNo

About this study

This phase I study is designed to establish the safety, maximally tolerated dose (MTD) and recommended phase II dose (RP2D) of the ERK inhibitor ulixertinib (BVD-523) when combined with the CDK4/6 inhibitor palbociclib.

This description comes directly from the study's public registry record.

Talk to the study team

Brian Burgess  ·  919-966-4432  ·  brian_burgess@med.unc.edu

Catherine Griffin  ·  919-966-4432  ·  catherine_griffin@med.unc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Lineberger Comprehensive Cancer CenterChapel Hill, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03454035