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Study identifier: NCT03422198 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Short Course Vaginal Cuff Brachytherapy in Treating Participants With Stage I-II Endometrial Cancer

Condition: Endometrial Clear Cell Adenocarcinoma · Endometrial Endometrioid Adenocarcinoma · Endometrial Serous Adenocarcinoma  ·  Sponsor: University of Utah

PhasePhase 3
Planned participants188
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

This randomized phase III trial studies short course vaginal cuff brachytherapy to see how well it works compared with standard of care vaginal cuff brachytherapy in treating participants with stage I-II endometrial cancer. Short course vaginal cuff brachytherapy, also known as internal radiation therapy, uses (over a shorter period) radioactive material placed directly into or near a tumor in the upper portion of the vagina to kill tumor cells. After completion of cohort 1 (108 participants), the protocol was expended to add a second cohort of 80 additional participants, and re-opened study recruitment.

This description comes directly from the study's public registry record.

Talk to the study team

Rachel Kingsford  ·  801-585-0115  ·  Rachel.Kingsford@hci.utah.edu

Always discuss trial participation with your own doctor first.

Locations (5)

Stanford Cancer CenterPalo Alto, California, United StatesCompleted
Loyola University Medical CenterMaywood, Illinois, United StatesRecruiting
MD AndersonHouston, Texas, United StatesRecruiting
Huntsman Cancer Institute/University of UtahSalt Lake City, Utah, United StatesRecruiting
Intermountain Medical Center / LDS HospitalSalt Lake City, Utah, United StatesCompleted

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Source record: clinicaltrials.gov/study/NCT03422198