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Study identifier: NCT03420339 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Stimulant Effects on Disruptive Behavior

Condition: Attention Deficit Hyperactivity Disorder · Problem Behavior  ·  Sponsor: Matthew J O'Brien, PhD, BCBA-D

PhasePhase 4
Planned participants10
Who can joinAll sexes, 48 Months to 12 Years
Healthy volunteersYes

About this study

The goal of this study is to determine the effects of stimulant medication on disruptive behavior, function, preference and choice; however, it is primarily methodological and will add to current research by establishing an effective evaluation of the impact of stimulant medication on these behaviors. Three behavior assessments for children and adolescents diagnosed with AD/HD who exhibit disruptive behavior will be conducted: 1. Preference assessments will be conducted to determine whether preference for social and nonsocial items and activities differs under medication and non-medication conditions. 2. Functional analyses will be conducted to determine whether stimulant medication has an effect on the frequency and function or purpose of disruptive behavior. 3. Choice assessments will be conducted to evaluate the impact of stimulant medication on impulse control/delay discounting. This study will be conducted in three phases. For each of the 5 to 10 participants there will be 8 total visits. The first 4 visits will entail a preference assessment, followed by a functional analysis. On visits 1 and 3, the participant will be asked to take his/her stimulant medication as is typically done; however, on visits 2 and 4, the participant will be asked to refrain from taking the medication. For visits 5-8, participants will continue to participate in preference assessments, but will also be presented with a choice arrangement with work and play. In the choice arrangement, partici…

This description comes directly from the study's public registry record.

Talk to the study team

Matthew J O'Brien, PhD  ·  319.384.9827  ·  matthew-j-obrien@uiowa.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Iowa Hospitals and ClinicsIowa City, Iowa, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03420339