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Study identifier: NCT03419260 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Electrographic Seizure Management and Neurobehavioral Outcomes in Critically Ill Children

Condition: Seizures  ·  Sponsor: Children's Hospital of Philadelphia

PhaseN/A
Planned participants2500
Who can joinAll sexes, 1 Month to 18 Years
Healthy volunteersNo

About this study

Electrographic seizures are common in critically ill patients leading to increased use of resource-intense continuous EEG monitoring for seizure identification and management. When identified, electrographic seizures are generally treated with anti-seizure medications, but there are very limited data available regarding optimal treatment in terms of the efficacy or safety of specific anti-seizure medications or overall management strategies. This is a single-center prospective observational study. The investigators aim to: (1) track critically ill patients undergoing clinically indicated EEG monitoring and seizure management to identify risk factors for electrographic seizures, (2) create prediction models guiding EEG monitoring resources to the patients at highest risk for seizures, and (3) evaluate our current management strategy in terms of safety.

This description comes directly from the study's public registry record.

Talk to the study team

Nicholas S Abend, MD  ·  215-590-1719  ·  abend@chop.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Children's Hospital of PhiladelphiaPhiladelphia, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03419260